UNEXPLAINED INFERTILITY
- It is where the cause remains unknown even after a complete infertility work up including semen analysis in the man and assessment of ovulation and tubal patency in the woman.
- Prevalence :Accounts for about 10% of causes of infertility, globally.
- Possible Causes : Abnormalities are likely to be present but are not currently detected by commonly performed investigations.
These may include:
- Poor egg quality
- Increased DNA fragmentation in the sperm
- Failure of sperm to fertilize the egg
- Mild endometriosis etc
Management :
Lifestyle modification
Ovulation induction for 3 to 6 cycles
Ovulation induction with IUI for 3 to 6 cycles
IVF treatment
UTERINE MALFORMATION
- Uterine malformations are congenital defects of a woman’s uterus occurring in about 5% of women
Types of malformation
Arcuate :
- Uterus appears normal from the outside but has a very small indentation protruding from the inner wall of the cavity. This is generally unproblematic.
Bicornuate :
- The uterus appears heart shape with a deep indentation starting at the top of the uterus.
Septate :
- The uterus appears normal from outside but contains an internal wall or septum that divides the uterine cavity into two.
Didelphys :
- double uterus where the two halves of the uterus remain completely separate
Unicornuate :
- Only one half of the uterus is well developed.
Diagnosis :
- Mostly discovered during investigation for infertility as they are usually asymptomatic
- 3D ultra sound
- HSG
- MRI
- Diagnostic hysteroscopy
Treatment:
Medical Management:
Surgical Management:
- Only septate uterus needs to be treated the usual procedure performed being hysteroscopic septal resection.